台灣 FDA 於 2013-11-18 規定限量為 0.01%,且不得使用於接觸黏膜部位產品。
在歐洲化妝品法規中,授權使用的最大濃度為 0.0015% (15 ppm)。
美國CIR(cosmetic ingredient review)認為,在濃度低於 100 ppm 並且可以證明所使用的濃度不會引起皮膚過敏反應,在許多使用後馬上沖洗掉的產品是安全的。已知對這些成分敏感的人可以選擇避免使用。
2-Methyl-4-isothiazolin-3-one/ Methylisothiazolinone/ NEOLONE 950/ MIT
Kathon CG, Methylchloroisothiazolinone & Methylisothiazolinone/ 5-chloro-2-methyl-4-isothiazolin-3-one / 2-methyl-4-isothiazolin-3-one, Microcare IT
As a preservative, it is only recommended to add it to products that need to be washed away with water immediately after use, such as facial cleanser or shampoo. If it is used in products that do not need to be washed away, if the content is high, methyl isothiazolinone is easy to cause skin sensitivity.
On November 18, 2013, FDA of Taiwan stipulated that the limit is 0.01% and should not be used in products contacting mucous membrane.
In European cosmetic regulations, the maximum concentration authorized for use is 0.0015% (15 ppm).
American CIR (cosmic reddit review) believes that when the concentration is lower than 100 ppm and it can be proved that the concentration used will not cause skin allergic reaction, many products washed off immediately after use are safe. People who are known to be sensitive to these ingredients may choose to avoid them.
On November 18, 2013, FDA of Taiwan stipulated that the limit is 0.01% and should not be used in products contacting mucous membrane.
In European cosmetic regulations, the maximum concentration authorized for use is 0.0015% (15 ppm).
American CIR (cosmic reddit review) believes that when the concentration is lower than 100 ppm and it can be proved that the concentration used will not cause skin allergic reaction, many products washed off immediately after use are safe. People who are known to be sensitive to these ingredients may choose to avoid them.
ref.